Yasuo Urata Selected Research

Telomerase (Telomerase Reverse Transcriptase)

4/2022	Overexpression of Adenovirus E1A Reverses Transforming Growth Factor-β-induced Epithelial-mesenchymal Transition in Human Esophageal Cancer Cells.
10/2021	Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles.
5/2021	Telomerase-specific oncolytic immunotherapy for promoting efficacy of PD-1 blockade in osteosarcoma.
9/2020	Elimination of MYCN-Amplified Neuroblastoma Cells by Telomerase-Targeted Oncolytic Virus via MYCN Suppression.
6/2020	Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer.
10/2018	Integrated fluorescent cytology with nano-biologics in peritoneally disseminated gastric cancer.
1/2018	Detection of circulating tumor cells in cervical cancer using a conditionally replicative adenovirus targeting telomerase-positive cells.
11/2017	Therapeutic Cell-Cycle-Decoy Efficacy of a Telomerase-Dependent Adenovirus in an Orthotopic Model of Chemotherapy-Resistant Human Stomach Carcinomatosis Peritonitis Visualized With FUCCI Imaging.
8/2017	Eradication of melanoma in vitro and in vivo via targeting with a Killer-Red-containing telomerase-dependent adenovirus.
5/2017	Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients.

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Yasuo Urata Research Topics

Disease

56	Neoplasms (Cancer) 06/2022 - 09/2004
12	Infections 06/2022 - 04/2005
7	Osteosarcoma (Osteogenic Sarcoma) 05/2021 - 06/2011
6	Neoplasm Metastasis (Metastasis) 06/2022 - 03/2015
6	Circulating Neoplastic Cells 05/2018 - 10/2009
5	Stomach Neoplasms (Stomach Cancer) 06/2022 - 01/2016
5	Lung Neoplasms (Lung Cancer) 05/2018 - 02/2006
4	Lymphatic Metastasis 03/2015 - 10/2006
3	Sarcoma (Soft Tissue Sarcoma) 01/2021 - 04/2011
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2017 - 02/2006
3	Virus Diseases (Viral Diseases) 12/2011 - 04/2011
2	Rectal Neoplasms (Rectal Cancer) 10/2021 - 03/2015
2	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 06/2010
2	Melanoma (Melanoma, Malignant) 08/2017 - 04/2016
2	Triple Negative Breast Neoplasms 01/2017 - 12/2016
2	Colonic Neoplasms (Colon Cancer) 01/2016 - 03/2015
2	Head and Neck Neoplasms (Head and Neck Cancer) 04/2009 - 01/2009
2	Carcinogenesis 01/2008 - 03/2007
1	Esophageal Neoplasms (Esophageal Cancer) 04/2022
1	Fatigue 01/2022
1	Anemia 01/2022
1	Hypertriglyceridemia 01/2022
1	Vomiting 01/2022
1	Abdominal Pain (Pain, Abdominal) 01/2022
1	Glaucoma 12/2020
1	Surgical Wound 12/2020
1	Fibrosis (Cirrhosis) 12/2020
1	Blister (Bulla) 12/2020
1	Neuroblastoma 09/2020
1	Adenocarcinoma of Lung 05/2018
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2018
1	Ascites 11/2017
1	Peritonitis 11/2017
1	Carcinoma (Carcinomatosis) 11/2017
1	Leukemia 09/2017
1	Breast Neoplasms (Breast Cancer) 08/2016
1	Neoplasm Micrometastasis 01/2016
1	Fibrosarcoma 05/2015
1	Disease Progression 04/2015

Drug/Important Bio-Agent (IBA)

49	Telomerase (Telomerase Reverse Transcriptase)IBA 04/2022 - 09/2004
11	Green Fluorescent ProteinsIBA 10/2018 - 09/2004
7	Proteins (Proteins, Gene)FDA Link 10/2021 - 11/2010
5	Biological ProductsIBA 06/2022 - 02/2008
5	Pharmaceutical PreparationsIBA 01/2022 - 07/2006
5	adenovirus receptorIBA 01/2021 - 04/2005
5	Methylnitronitrosoguanidine (MNNG)IBA 01/2021 - 04/2011
5	Indicators and Reagents (Reagents)IBA 03/2017 - 04/2011
4	Paclitaxel (Taxol)FDA LinkGeneric 06/2022 - 01/2016
4	DNA (Deoxyribonucleic Acid)IBA 05/2018 - 06/2009
4	Biomarkers (Surrogate Marker)IBA 01/2018 - 10/2009
4	Red Fluorescent ProteinIBA 12/2016 - 01/2015
4	ElementsIBA 02/2009 - 09/2004
3	Messenger RNA (mRNA)IBA 12/2013 - 04/2011
2	YM753 compoundIBA 01/2022 - 12/2020
2	Histone Deacetylase InhibitorsIBA 01/2022 - 02/2006
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2016
2	Adenosine Triphosphate (ATP)IBA 01/2020 - 05/2012
2	Estrogens (Estrogen)FDA Link 01/2017 - 12/2016
2	Progesterone FDA LinkGeneric 01/2017 - 12/2016
2	Internal Ribosome Entry SitesIBA 02/2006 - 09/2004
1	Interleukin-6 (Interleukin 6)IBA 06/2022
1	CytokinesIBA 06/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 04/2022
1	TransferasesIBA 01/2022
1	DepsipeptidesIBA 01/2022
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2022
1	Therapeutic UsesIBA 10/2021
1	Immune Checkpoint InhibitorsIBA 05/2021
1	Ophthalmic Solutions (Eye Drops)IBA 12/2020
1	CollagenIBA 12/2020
1	HMGB1 Protein (HMG1)IBA 01/2020
1	Anaplastic Lymphoma KinaseIBA 05/2018
1	Keratins (Keratin)IBA 01/2018
1	AntibodiesIBA 01/2018
1	Epithelial Cell Adhesion MoleculeIBA 05/2017
1	NestinIBA 03/2017
1	Neutralizing AntibodiesIBA 11/2016
1	Sepharose (Agarose)IBA 01/2016
1	Photosensitizing Agents (Photosensitizers)IBA 01/2016
1	Small Interfering RNA (siRNA)IBA 01/2016
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2016
1	Cisplatin (Platino)FDA LinkGeneric 01/2016

Therapy/Procedure

19	Therapeutics 06/2022 - 04/2005
8	Oncolytic Virotherapy 01/2021 - 03/2007
7	Drug Therapy (Chemotherapy) 06/2022 - 01/2016
3	Radiotherapy 01/2021 - 01/2012
3	Transplantation 11/2017 - 08/2016
3	Aftercare (After-Treatment) 11/2017 - 03/2015
3	Lasers (Laser) 08/2017 - 01/2016
3	Computer-Assisted Surgery (Image Guided Surgery) 08/2011 - 10/2006
2	Chemoradiotherapy 12/2013 - 01/2012
2	Injections 05/2012 - 11/2009
2	Laparotomy 01/2008 - 10/2006
1	Intravenous Infusions 01/2022
1	Immunotherapy 05/2021
1	Filtering Surgery 12/2020
1	Precision Medicine 10/2018
1	Stents 01/2018
1	Biological Therapy 11/2016
1	Photochemotherapy (Photodynamic Therapy) 01/2016